Materials Science & NanoEngineering
Professor of Bioengineering
MSNE Seminar Series- Prof. Gang Bao "Engineering Multifunctional Nanoparticles for Disease Detection and Treatment" (450/451/500)
Thursday, February 2, 2017
to 4:00 PM
180 Dell Butcher Hall
6100 Main St
Houston, Texas, USA
The integration of biomolecular engineering, nanotechnology and biology is expected to produce major breakthroughs in medical diagnostics and therapeutics. Due to the size-compatibility of nano-scale structures with proteins and nucleic acids, the design, synthesis and application of nanoprobes, nanocarriers and nanomachines provide unprecedented opportunities for achieving a better control of biological processes, and drastic improvements in disease detection, therapy, and prevention. Recent advances include the development of multi-functional nanoparticles, nano-structured materials and devices, and engineered nucleases for biological and medical applications.
In this talk, Dr. Bao will present the recent development and application of molecular imaging probes and nanoparticle carriers in his lab, including nanocrystal–based signal amplification for biomolecule detection, multi-modality PET/MR/fluorescence imaging contrast agent for disease detection, as well as nanoparticle-based strategies for drug/gene delivery. The opportunities and challenges in nanobioengineering are also discussed.
Biography of Gang Bao:
Dr. Gang Bao is the Foyt Family Chair Professor in the Department of Bioengineering, Rice University. He is also Director of Nanomedicine Center for Nucleoprotein Machines, a NH Nanomedicine Development Center (NDC) at Rice. Dr. Bao received his undergraduate and Master’s degrees from Shandong University in China, and his PhD from Lehigh University. Dr. Bao is a Fellow of the American Association of Advancement in Science (AAAS), a Fellow of the American Society of Mechanical Engineers (ASME), a Fellow of the American Physical Society (APS), and a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). Dr. Bao’s current research is focused on the development of nanotechnology and biomolecular engineering tools for biological and disease studies, including molecular beacons, magnetic nanoparticle probes, quantum dot bioconjugates, protein lagging/targeting methods, and engineered nucleases. These approaches have been applied to the diagnosis and treatment of cardiovascular diseases and cancer, and the development of gene correction approaches for treating single-gene disorders.